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ImmunoCAP® ISAC and Microtest for multiplex allergen testing in people with difficult to manage allergic disease: a systematic review and cost analysis. A combination of innovative biochip technology with cutting edge research in molecular allergology has resulted in ImmunoCAP® ISAC – the most advanced in. The immuno-solid phase allergen chip (ISAC) test (Thermo Fisher ImmunoCAP ISAC) is a microarray assay system designed to assay specific.
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Health Technology Assessment, No. A systematic review was conducted to summarise the evidence on the clinical effectiveness and cost-effectiveness of ImmunoCAP ISAC and Microtest for multiplex allergen testing in people with allergic disease. Development of search strategies followed the recommendations of the CRD guidance for undertaking reviews in health care. Candidate search terms were identified from target references, browsing database thesauri e.
These scoping searches were used to generate test sets of target references, which informed text mining analysis of high-frequency subject indexing terms using EndNote X7 reference management software Thomson Reuters, CA, USA. Strategy development involved an iterative approach testing candidate text and indexing terms across a sample of bibliographic databases, aiming to reach a satisfactory balance of sensitivity and specificity.
Search strategies were developed specifically for each database. The following key conference proceedings, were identified in consultation with clinical experts, and were screened for the last 5 years where available:. No restrictions on language or publication status were applied. Searches took into account generic and other product names for the intervention. See Appendix 1 for all search strategies. References in retrieved articles were checked for additional studies.
Adults and children with difficult to manage allergic disease who are being assessed in secondary or tertiary care settings. Owing to the paucity of available data, studies conducted in populations not specified as polysensitised or having difficult to manage allergic disease were also included.
All presentations of allergic disease respiratory, skin, gastrointestinal, anaphylaxis were eligible for inclusion. The comparator for this assessment was current standard care, which included allergy-focused clinical history, alternative tests of IgE antibody status single IgE antibody testingtests of clinical reactivity such as skin prick testing or allergen challenge testing or a combination of these approaches. There were no restrictions on study design.
Randomised controlled trials RCTscontrolled clinical trials, other comparative studies e. Observational study designs were eligible for inclusion only if they reported measures of additional diagnostic information provided by multiplex allergen testing; studies that assessed only concordance between multiplex allergen testing and single IgE antibody testing or other tests were not included.
No studies of this type were identified. The inclusion criteria were expanded to osac studies that reported direct comparisons of diagnostic accuracy between single IgE testing and multiplex allergen testing, using SPTs or allergen challenge tests immunoczp the reference standard.
Studies of this type were included with the aim of providing some indication of the performance of multiplex allergen testing, compared with current single IgE antibody testing practice, for predicting clinical response. Data of this type may inform the question of whether or not multiplex testing might, in some circumstances, replace single IgE testing as well as helping to guide possible future research recommendations.
Two reviewers MW and SL independently screened the titles and abstracts of all reports identified by searches and any discrepancies were discussed and resolved by consensus. Full copies of all studies deemed potentially relevant were obtained and the same two reviewers independently assessed these for inclusion; any disagreements were resolved by consensus.
Details of studies excluded at the full paper screening stage are presented in Appendix 3. The principal investigators of completed trials identified through searches of clinical trials registries that appeared to meet our inclusion criteria but for which no publication could be identified were contacted and asked to provide publication details or unpublished data.
Data were extracted on the following: SPT, OFC, single IgE ; details of the reference standard test diagnostic accuracy studies only ; outcome measures included change to treatment or treatment plan, e. Data were extracted by one reviewer, using a piloted, standard data extraction form, and checked by a second MW and SL ; any disagreements were resolved by consensus. Full data extraction tables are provided in Appendix 2. This tool has been designed to focus on elements of study design that we considered relevant to this specific study type, and is based upon the structure of the QUADAS-2 im,unocap.
The results of the quality assessment have been used for descriptive purposes to provide an evaluation of the overall isaac of the included studies and to provide a transparent method of recommendation for design of any future studies.
Quality immunocxp was undertaken by one reviewer and checked by a second reviewer MW and SL and any disagreements were resolved by consensus. The applicability of studies to current UK practice was also considered and a narrative description of potential applicability issues is provided.
The results of the risk-of-bias assessments are summarised and presented in tables and graphs in the results of the systematic review see Study quality and are presented in full, by study, in Appendix 4. However, because iisac review identified a small number of studies with between-study variations in participant characteristics allergy historymultiplex allergen testing methods, allergens tested for, standard care comparators, and outcomes assessed, we did not consider meta-analyses to be appropriate and have provided a structured narrative synthesis.
The results of studies included in this review are summarised by outcome type clinical, change to management and diagnostic accuracy and are further stratified by allergen type food and aeroallergens.
ImmunoCAP ISAC – When you need the bigger picture in allergy
The results of individual studies are summarised in text and tables. The results of studies providing comparative accuracy data are also illustrated in receiver operating characteristic ROC space immunocsp.
The searches of bibliographic databases and conference abstracts identified references. After initial screening of titles and abstracts, were considered to be potentially relevant and ordered for full paper screening; of these, 20 were included in the review 30 — 49 and one 50 could not be obtained.
All potentially relevant studies cited in documents supplied by the test manufacturers had already been identified by bibliographic database searches.
ISAC Test, ISAC Testing & ISAC Testing in London
Additional data, relating to the study by Hermansson et al. Figure 1 shows the flow of studies through the review process, and Appendix 3 provides details, with reasons for exclusions, of all publications excluded at the full paper screening stage.
Based on the searches and inclusion screening described above see Search strategy and Inclusion and exclusion criteriaabove20 publications, 30 — 49 of 15 studies, were included in the review; the results section of this report cites studies using the primary isacc and, where this isc different, the publication in which the referenced data were reported.
Two of the included studies 3940 were conducted in the UK and, where reported, the remaining studies were conducted in other European countries; one study 47 did not report location. Of the 15 included studies, four were funded by, 3846 or received reagents and isaf 39 or testing services 45 from, the manufacturer. Five studies were publicly funded 3242 — 4449 and six studies 333637404147 did not report funding sources. Full details of funding are reported in the baseline study details tables see Appendix 2Tables A—C.
We did not identify any studies of Microtest which met the inclusion criteria for this review. We did not identify any studies that reported clinical outcomes i. None of the five studies 3233373840 reported the inclusion of patients with difficult to manage allergic disease; one study 40 reported inclusion criteria which may have been consistent with this classification moderate to severe eczema and multiple food allergies ; however, this study 40 was reported only as a conference abstract and immunlcap provided very limited details of participants.
One study 40 was conducted in the UK, two studies 3237 were conducted in Spain, and one study was conducted in each of Finland 33 and Italy. None of these studies reported test accuracy data.
One study 39 was conducted in the UK, one study 38 was conducted in Italy and one study 36 did not report location. None of the eight studies 41 — 4749 reported the inclusion of patients with difficult to diagnose and manage allergic disease, or described inclusion criteria that could be considered consistent with this jmmunocap e.
None of the studies was conducted in the UK, seven studies 41 — 4649 were European and one study 47 issac unreported. Full details of the characteristics of study participants, study inclusion and exclusion criteria, and intervention and comparator or reference standard are reported in the data extraction tables presented in Appendix 2 see Tables A—E.
One hundred and forty-eight full-text articles were retrieved: In all but two cases, 5152 these studies reported no relevant outcomes. Further details of the excluded full papers and the reasons for exclusion can be found in Appendix 4. One study 50 could not be obtained.
Seven studies investigated changes to treatment or management outcomes. The methodological quality of this study 36 was assessed using the CASP cohort tool. The methodological quality of these studies was assessed using a tool jmmunocap specifically for this review, which was based on the structure of QUADAS Risk of bias and concerns regarding applicability are summarised in Tables 2 and 3 and Figure 2 ; full assessments for each study are provided in Appendix 4.
Risk of bias for included diagnostic studies change to management or treatment: Although this review included patients with any allergy, the primary objective was to assess the clinical effectiveness of multiplex allergen testing in people with complex or difficult to manage allergies, in UK health-care settings.
Studies that did not specify that they included iszc with difficult to manage allergic disease, or describe inclusion criteria which could be considered consistent with this classification e. Studies that were conducted in non-UK settings and which assessed allergens considered unlikely to be relevant to UK populations e. The small observational study 36 that was assessed using the CASP cohort tool for risk of bias was reported only as conference abstract; therefore, risk of bias was largely unclear owing to lack of study details.
Immunpcap of bias across included diagnostic studies accuracy. One study 47 was reported only as a conference abstract. The main potential sources of bias were in relation to participant selection and application of the index test. In all cases this was because diagnostic thresholds were not prespecified, but were optimised using ROC analyses in the same population that was used to assess test performance, an approach that is likely to result in inflated estimates of test performance.
As was the case for studies of change to management, treatment or diagnosis, studies that did not specify that they included participants with difficult to manage allergic disease or describe inclusion criteria that could be considered consistent with this classification e.
Confidential information has been removed Johannes Savolainen, personal communication.
ISAC Test: 112 Allergy Tests in one tiny blood sample!
The Hermansson study 33 did not report any information on clinical outcomes following changes to dietary management. Noimark and Harnik 40 investigated 12 children selected from patients attending an East London allergy clinic no details of the selection criteria were reported. Noimark and Harnik 40 did not report the number of food reintroductions that occurred following testing or isca outcomes of any changes to dietary management. Two studies 3738 assessed the views of clinicians on whether or not Iac ISAC testing provided information useful in the management of patients.
Two studies investigated the effect on diagnostic classification of adding ImmunoCAP ISAC testing to the standard diagnostic work-up of people with allergic disease. This study 36 included only nine participants who received a total of 31 courses of SIT no details of diagnosis were reported.
However, importantly, none of the studies that we identified reported any information on clinical outcomes subsequent to changes in treatment or management based on ImmunoCAP ISAC.
Three studies report the usefulness of ImmunoCAP ISAC for discriminating allergens that are structurally similar and are recognised by the same IgE antibody cross-immunoreactive ; this discrimination appears to be particularly useful for identifying the cause of food allergies.
However, it should be noted that the addition of ImmunoCAP ISAC also resulted in the identification of large numbers of sensitisations that were not considered to be associated with the anaphylaxis, that is, large numbers of clinically false-positive test results or sensitisations associated with other allergic conditions such as rhinitis. Six studies 414244464749 were identified which compared the accuracy of ImmunoCAP ISAC to existing diagnostic tests SPT or single IgE tests in people with food allergies; two studies 4345 were identified of people with allergies to aeroallergens.
De Swert et al. Cut-off values were reported separately for each test and OFC testing was used as the reference standard. The diagnostic accuracy of ISACisa used to measure three individual egg components Gal d1 or Gal d2 or Gal d3was compared with the accuracy of single IgE tests egg yolk or egg white and compared with the accuracy of SPTs egg white extract or raw egg white or boiled egg white or egg yolk extract or raw egg yolk ijmunocap boiled egg yolk.
Results for raw egg were similar to those for boiled egg. In general, single IgE performed similarly to SPT both measured whole extractswhereas ISAC gave much more variable results for the three different components measured. No measure of the overall diagnostic performance of ISAC all components combined was reported. The results were very variable between tests.
All three ISAC 51 components had low sensitivity ranging from Single Isav testing and skin prick testing had comparable specificity For both methods, a positive result was defined as positive lsac at least one component or whole allergen; the cut-off values used to define positivity for individual components and allergens were not reported. OFC testing was used as the reference standard.
A New Quassinoid from Crude Quassin-extract of Quassia amara Article. Quassinoids from Picrasma Crenata Journal of Asian Natural Products Research. A new quassinoid, 2-dihydroailanthone, has been isolated from the bark of Ailanthus glandulosa. Its structure was established on the basis of spectroscopic data. ISSN: Online Available at International Journal of Herbal Medicine. Quassinoids and Their Chemotaxonomic Significance.
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Tetracyclic quassinoid skeletons 2 and 22 with six correct chiral centres common to numerous quassinoids are constructed from S -carvone and 3-methylsulfolene by a step and step reaction sequence involving highly regioselective and stereocontrolled reactions.
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A new antimalarial quassinoid from Simaba orinocensis.
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A new antimalarial quassinoid from Simaba orinocensis.
Journal of the Chemical Society, Perkin Transactions 1. Synthesis of optically active tetracyclic quassinoid skeleton. Back to tab navigation Download options Please wait Synthesis of optically active tetracyclic quassinoid skeleton T.
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Asus P7P55D PRO Pdf User Manuals. View online or download Asus P7P55D PRO User Manual. No part of this manual, including the products and software described in it, may be Thank you for buying an ASUS® P7P55D-E PRO motherboard!. Asus P7P55D Pro User Manual (MB) Download BIOS , ACPIa, Multi- Language BIOS, ASUS EZ Flash 2, ASUS CrashFree BIOS3.
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Product warranty or service will not be extended if: DO NOT throw mnaual motherboard in municipal waste. This product has been designed to enable proper reuse of parts and recycling. If possible, disconnect all power cables from the existing system before you add a device.
Where to find more information Refer to the following sources for additional information and for product and software updates. Refer to the ASUS contact information. Optional documentation Your product package may include optional documentation, such as warranty flyers, that manusl have been added by your dealer. Conventions used in this guide To ensure that you perform certain tasks properly, take note of the following symbols used throughout this manual.
Information to prevent injury to yourself when trying to complete a task. Information to prevent damage to the components when trying to complete a task. Adjustable CPU voltage at 0.
Before you start installing the motherboard, and hardware devices on it, check the items in your package with the list below. Refer to page and for details. Refer to page for details. ON, in sleep mode, or in soft-off mode. This is a reminder that you should shut down the system and unplug the power cable before removing or plugging in any motherboard component. The illustration below shows the location of the onboard LED. The edge with external ports goes to the rear part of the chassis as indicated in the image below.
Lift the load lever in the direction of the arrow until the load plate is completely lifted. Close the load plate Aand then push down the load lever Bensuring that the front edge of the load plate slides under the retention lock C. Insert the load lever under the retention tab. Rotate each fastener counterclockwise. Pull up two fasteners at a time in a diagonal sequence to disengage the heatsink and fan assembly from the motherboard.
Carefully remove the heatsink and fan assembly from the motherboard. DDR3 modules are developed for better performance with less power consumption. Support the DIMM lightly with your fingers when pressing the retaining clips. The DIMM might get damaged when it flips out with extra force. Remove the DIMM from the socket. Expansion slots In the future, you may need to install expansion cards. The following subsections describe the slots and the expansion cards that they support.
Ensure to unplug the power cord before adding or removing expansion cards.
Failure to do so may cause you physical injury and damage motherboard components. Refer to the figure below for the location of the slots. See page for details. Read the following information before you change the switch settings.
ASUS P7P55D PRO USER MANUAL Pdf Download.
Refer to section 3. Connect to Stereo Speakers Connect to 2. This prevents incorrect insertion when you connect the IDE cable. Never connect a cable to the USB connectors.
Doing so will damage the manuao This connector is for a serial COM port. Connect the serial port module cable to this connector, then install the module to a slot opening at the back of the system chassis.
The COM module is purchased separately. By default, this connector is set to [HD Audio].
ASUS P7P55D PRO User Manual
Refer to the labels on the Q-Connector to know the detailed pin definitions, and then match them to their respective front panel cable labels.
This user-friendly design provides an intuitional way to locate the root problem within a second. Be sure that all switches are off. Connect the power cord to the power connector at the back of the system chassis. Connect the power cord to a power outlet that is equipped with a surge protector. Turn on the devices in the following order: Refer to the corresponding sections for details on these utilities. Mankal the onscreen instructions to complete the update auss.
Always update the utility to avail all its features.
If you want to use the newer BIOS file, download the file at support. Save the BIOS file to a bootable floppy disk. When you start up the computer, the system provides you with the opportunity to run this program. Otherwise, POST continues with its test routines. This makes more efficient use of the PCI bus as fewer transactions are needed manjal the transfer of a particular amount of data. Ai Tweaker menu The Ai Tweaker menu items allow you to configure overclocking-related items.
Be cautious when changing the settings of the Ai Tweaker menu items. Incorrect field values can cause the system to malfunction.
Xtreme Design – Hybrid Series, Designed to Perform
Profile function to overclock the DRAM. We recommend you install the DIMMs with the voltage requirement below 1. The values range from 1. Refer to the table below for details. Scroll down to display the following items: The valid value ranges vary according to your CPU model. Setting wrong values in below sections may cause system to malfunction.
Sets to [Silent] to minimize the fan speed for quiet CPU fan operation. Enables the full screen logo display feature. Select this item to clear the user password. For more details, refer to section 3. Select Ok to load default values. The contents of the support DVD are subject to change at any time without notice. Visit the ASUS website at www. The Manual folder of the support DVD appears. Double-click the folder of your selected software. The AI Suite main window appears.
The AI Suite icon appears in the Windows notification area. The various fan profiles offer flexible controls of fan speeds to achieve a quiet and cool system environment. It detects the current computer loading and intelligently adjusts the power in real-time. With auto phase switching for components, the EPU automatically provides the most appropriate power usage via intelligent acceleration and overclocking.
Within a few seconds of powering on your computer, you will be at the Express Gate menu where you can start the web browser, Skype, or other Express Gate applications.
P7P55D PRO | Motherboards | ASUS USA
Follow the screen instructions to complete installation. Click the Auto Tuning tab and then click Start. You can also click More Setting first to configure more overclocking parameters before starting auto-overclocking.
After the easy setup, Turbo Key can boost performances without interrupting ongoing work or games—with just one touch! For optimal performance, install identical drives of the same model and capacity when creating a disk array. Install the SATA hard disks into the drive bays. A small triangle marks the selected drive. From the utility main menu, select 4.
The following warning message appears: USB Floppy, and then select Properties from the pop-up window. The name of the USB floppy disk drive varies with different vendors. Browse the contents of the RAID driver disk to locate the file txtsetup. A window appears, allowing you to select the program for opening the oem file.
Use Notepad to open the file. For Windows Vista, select Uninstall. Turn off your computer.
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Scale and scalability have been recurring topics in visual computing. In recent years data complexity concerning volume, veracity, velocity, and variety has increased considerably.
We present a technique, which adaptively, based on the current scale level, nonlinearly and seamlessly adjusts the color scheme to depict or distinguish the currently best visible structural information. The approach re-scales and normalizes user input according to visual change, and also visually communicates this re-scaling and normalization. Another example deals with multiscale visualization and scale-adaptive modification of DNA nanostructures.
This new way of observing, interacting with, and creating DNA nanostructures enables domain experts to approach their work in any of the available semantic abstraction levels, supporting both low-level manipulations and high-level visualization and modifications. Research challenges and directions with respect to scale and scalability are sketched at the end of the talk. His research interests include computer graphics, visualization, and visual computing.
The group performs basic and applied research in all areas of visualization He is a scientific proponent and key researcher of the VRVis research center. The center performs applied research in visualization, rendering, and visual analysis. He became a fellow of the Eurographics association in With the rise of AI and Data Science supportive technology increasingly takes decisions on our behalf, such as which data to share with whom or who to contact if help is needed.
Birna van Riemsdijk – TU Delft we develop theory and technology for creating software that understands and adapts to our norms and values in taking such decisions, which we call Socially Adaptive Computing.
In this presentation we focus on one such agent, called HabINT, that aims at supporting people in their daily activities. We give an overview of the knowledge representation formalism that HabINT uses to reason about norms, values, and habitual behaviour. The Naviterier project at the HCI Center, Department of Computer Graphics and Interaction in Prague aims at supporting visually impaired people in their navigation-related tasks developing dedicated software.
In the presentation, we discuss how biolovie integrate the technology from kostcr groups to provide even stronger support for visually impaired people even if they develop mental impairments related to aging. Her publications address cognitive processes and concepts such as negotiation, teamwork and the dynamics of individual agents and organizations.
In all her research lines Catholijn has adopted a value-sensitive approach. In particular, she works towards intelligent agents that can interact with their users in value-conflicting situations when also meta-values no longer solve the situation.
He has been working on interactive agents for habit supports and knowledge structures for human behaviour representation. Jak se tam dostal? Opinions vary on what is the best image a machine can synthesize. In this talk I will discuss some possible answers: First, physical accuracy has been a classic and quantifiable objective, and I will give an example of a technique to robustly compute unbiased images. Another important aspect to discuss is computational efficiency. I biooogie explain how rasterization abilities of modern graphics hardware can be used to introduce global illumination at interactive frame rates.
I will discuss the particular challenge of computing what is the best stereo image using a perceptual model. I will discuss examples of using Internet image collections to guide users when realizing what they imagine. Finally, images have commonly been synthesized from complete information.
I will discuss some alternatives, where only incomplete information is available and extrapolation from sparse example images is made to achieve better coverage by many images.
Recent years have seen a number of breakthroughs that indicate a renewed interest ibologie the possibilities of creative machines. Game-playing agents developed by Google Deepmind are capable of learning surprisingly original solutions. Deep learning allows anyone to make paintings in the style of famous artists. Other computational tools are now bioloogie to inspire and guide human designers. In this talk, we will look at examples of creative machine learning, consider to what extent they qualify as being creative, and discuss what additional steps would be necessary for artificial creativity.
Stefan Leijnen is lecturer and researcher kstce artificial intelligence at the Amsterdam University of Applied Sciences. His primary research interest is in understanding how novelty arises from dynamical systems, particularly in neural networks.
More generally, he is interested in generative computational methods, deep learning and epistomology. He has recently founded the Asimov Institute, an independent research organization aiming to develop technological solutions for creativity and control of machine learning.
While it is clear that the use of computer simulations has a positive effect on learning when compared to instruction without computer simulations, there is still room for improvement to fully realize their benefits for learning. Haptic technologies can fulfill the educational potential of computer simulations by adding the sense of touch.
Visuohaptic simulations may not only help students visualize abstract or invisible concepts, but they may also have the capability of enriching the learning experience and enhancing retention.
Biologie II. v kostce: zoologie, biologie člověka – Hana Hančová – Google Books
Our argument is based on the idea that haptic technology can support embodied learning by grounding movements during the learning process as learners manipulate and interact with virtual objects via the haptic interface.
Still, previous work that has compared visual simulations versus visuohaptic simulations has not reported conclusive results. This research seminar provides an overview of a design-based research program that investigates effectiveness of the use of visuohaptic simulations to support the understanding of difficult concepts in science.
We explored a sequencing approach to address the possibility of visual information undermining tactile information, when presented together. Our preliminary studies have shown promising results. Synthesizing natural scenes with realistic vegetation has always been an interesting research topic in computer graphics. As frequent objects in our daily life, vegetation is required in almost all virtual sceneries, ranging from single plants and trees to wide outdoor ecosystems. The human visual system is perfectly trained to see any imperfections and irregularities.
Therefore, the appearance and the inhomogeneous structure of plants still pose many challenges to computer graphics researchers. Although rich and detailed virtual environments become popular in applications like games, movies or urban visualization, storing and transmitting as well as modeling or rendering such objects with full detail is beyond the capabilities even of modern graphics hardware.
Figure 1 shows a small forest with large amount of detail modeled through a modern reconstruction algorithm. This talk will cover several latest algorithms and techniques in modeling vegetation in computer graphics. In particular, we will focus on advances in 1 procedural and inverse-procedural modeling, 2 biologically-based approaches, and 3 user-assisted approaches for vegetation modeling.
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Rozhovor o algoritmu StyLit s doc. Visualization and Visual Computing use computer-supported, interactive, visual representations of abstract data to amplify cognition. In recent years data complexity and variability has increased considerably. This is due to new data sources as well as the availability of uncertainty, error and tolerance information. Instead of individual objects entire sets, collections, and ensembles are visually investigated. This raises the need for effective comparative visualization approaches.
Visual data science and computational sciences provide vast amounts of digital variations of a phenomenon kodtce can be explored through superposition, juxtaposition and explicit difference encoding.
Biologis few examples of comparative approaches coming from the various areas of visualization, i. Analysis techniques ksotce combine visualization and simulation to assist decision making in flooding scenarios, indoor lighting design and city planning will be discussed.
Given the amplified data variability, comparative visualization techniques are likely to gain in importance in the future. Research challenges, directions, and issues concerning this innovative area are sketched at the end of the talk. Hudba v Kingdom Come: Appearance Transfer for Fluid Animations.
Decomposing Time-Lapse Paintings into Layers. Animation Optimized Bounding Volume Hierarchies. Coherent Hierarchical Culling for Ray Tracing. In this talk I describe methods to capture the real world around us using cheap commodity 3D-cameras such as the Microsoft Kinect or any of its successors.
These cameras deliver 30 depth images per second, but each at only low quality. Yet, with the fusion of such a depth image stream, 3D-scans of decent quality can be made. I will describe extensions that make it possible to scan large scenes and show results from scanning sessions in an excavation site in Turkey.
Another extension handles the realtime capturing of deformable objects such as faces, hands, or bodies.
Finally, I will show a very recent new realtime approach combining depth and RGB-data to increase the resolution of the captured geometry. We present a flexible approach that can deal with generic objects, both textured and texture-less.
The key new concept is a learned, intermediate representation in form of a dense 3D object coordinate estimate paired with a dense object labelling. Random forests are exploited to predict 3D object coordinates and object probability from local image patches.
Tracking is based on the particle filter framework for which we designed efficient proposal distributions in order to efficiently sample the six dimensional parameter space of object poses. The proposed approach allows for real-time tracking and is very robust to changes in lighting and to occlusions.
Due to the immense parallel processing power of modern graphics hardware, ray tracing algorithms and applications on the GPU have koetce. Depsite several architectural challanges, real-time recursive ray tracing has become possible. More sophisticated global illumination algorithms however still pose major challanges for efficient implementations on the GPU. After a short introduction into the programming model and the processing flow of GPUs, recent advances in real-time ray tracing will be discussed.
These include acceleration data structures as well as a study of memory access and latency during intersection testing. In this context, the general problem of kostxe and approaches to improve thread utilization will also be presented. The talk closes with an overview of techniques to implement more sophisticated global illumination algorithms like path tracing, bi-directional path tracing and Metropolis light transport, while putting an emphasis on the open problems in this field.
Procedural modeling has proven to be is a powerful set of algorithms and techniques and it has been used for generation of a wide-variety of objects and effects. However, their definition is a tedious and non-intuitive task that is usually done either by experts, or by a trial and error approach. In this presentation, we will show some of our results in the field of inverse biollogie modeling where we attampt to find a procedural representation of an existing object or a scene.
Various examples of learning models from biology, urban models, and other procedural representations will be presented. Visual computing encompasses a multitude of subjects which have evolved around a common goal: Recently, appearance fabrication has emerged as an exciting topic in visual computing: In this talk, I will present my contributions to appearance manufacturing, discussing passive reflectance field displays and printed subsurface scattering.
Further, I will show how the use of rapid manufacturing techniques for computational photography enables refocusing images after they were taken. Mutual Communication in Navigation of Visually Impaired.
Computer Systems Design and Architecture (2nd Edition). Authors: Vincent P. Heuring · Harry F. Jordan. Publication: Cover Image. · Book. Computer Systems. This book is a systems oriented approach to modern computer architecture that is shaped by the design experience of the two engineers who built the first stored. Prentice Hall. Computer Systems. Design and Architecture. Vincent P. Heuring and. Harry F. Jordan. Department of Electrical and Computer Engineering.
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Showing of 13 reviews. Top Reviews Most recent Top Reviews. There was a problem filtering reviews right now. Please try again later. This book covers a lot of concepts but is very difficult to follow. The structure of the book is very confusing. Sometimes it introduces a more advanced topic out of left field and you have to hope it covers it in more depth later on. Dwsign details are left out as well. The questions in each chapter are not possible to answer just based on the readings.
I had to buy this book for a university course and has been very little help.
Computer Systems Design and Architecture by Vincent P. Heuring
It’s softback, and NOT color print, which makes figures slightly harder to interpret. Not terrible, as the hardback version only uses two colors black and bluebut it can make a difference. If you can find the hardback version used somewhere I might recommend that. If not, this gets the job done.
There syetem several misprints in the book, so the authors have posted an errata on their website. Be sure to print a copy and keep it on hand so you can double check for errors in problems you are assigned for class. This systemm doesn’t do a very good job of explaining the process to get from point A to point B. My class required it, and it shows, as the class does the same thing. Would not recommend for anybody that doesn’t already have a firm foundation with computer architecture.
This book was required for my computer system design class, but it is a pretty useful book. Filled with helpful diagrams and easy to read. One person found this helpful. The pages were literally falling out of the book when I got it out of the package. That sounds like it is in “good” condition to me. I did not like this book as a course text when I was in college and I still do not care for it as an engineering reference.
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Originally published by Editions de Seuil, France, as Peau Noire,. Masques Blanc . Frantz Omar Fanon, born on 20 July in Fort-de-France. Narration in Frantz Fanon’s Peau noire masques blancs: Some Reconsiderations . ANJALI PRABHU. Wellesley College. ABSTRACT. Frantz Fanon’s writings are. Background. Published in , Peau Noire, Masques Blancs (hereafter, PNMB) by Frantz Fanon is an impassioned analysis of the.
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Essay fanon – peau noire, masques blancs final essay | Lisa Õismäe –
Skip to main mmasques. Log In Sign Up. Essay fanon – peau noire, masques blancs final essay. In Peau noire, masques blancs what role does Fanon attribute to racism in the construction of French national identity? This work will endeavour to discuss Fanons opinion on origins of racism, how it is incarnated in society. Furthermore it will explore how it has developed masquee to the old-fashioned educational system and how colour prejudice affects both black and white people: As well as discuss whether it is possible for them to break free from their feelings of inferiority and superiority and become truly equal.
Fanon understood that racism is a result of a certain social influence and according to him it appears under certain social circumstances, for example colonialism: In colonised countries slaves were an important workforce due to the fact that they were the cheapest a land owner could get, therefore, the relationship between the white man and the black man was blncs inevitably one of a master and a slave. Normandie roto impression s.
In order for this to be accomplished, the black man had to be completely stripped of his history and culture, and consequently have it replaced with the new ideology. Embedded in the white mans ideology were their racial views which were then internalised into the new structure of society and culture franzt the frwntz man. What is crucial it that these values were introduced to the collective unconscious of the colonised society by means of literary element — the language.
File:Fanon Frantz Peau noire masques blancs pdf – Monoskop
When a black man speaks the language of the white man, Fanon argues, that he than accepts the racist ideologies and notions of superiority of the oppressor that dwell within the language. Furthermore, Fanon states that by speaking the white mans language he in turn rejects his own culture and betrays himself, and in doing so assimilates himself into a society where he is believed to be inferior. It is not surprising; however, as to speak the French language for the Antillean was to accept the world of a Frenchman.
Therefore in colonised countries, the adapted language became, in a manner, a doorway through which a power of proclamation of white superiority was implanted into the colonised mans unconsciousness. The supremacy of one race was asserted by racial stereotypes and colour prejudice propaganda, by a religion that has always associated black with evil and 3 Frantz Fanon, Peau noire, masques blancs P.
Over time this became dominant, present in all aspects of society. Inferiority only corresponds to the superiority. Thus, both white man and a black man are trapped in their own beliefs. For example a white man cannot see a black man past his colour. White men impose inferiority of a black man by treating them as children or not very educated.
Furthermore the author mentions that it is not to hurt black person, they do it out of ignorance and lack of interest. White men are not interested in black people. It is pure ignorance.
On the other hand the black man is trapped in his own image; he believes that he has no chance to be white. By this he means that if one does not think he is superior, the other will not think he is inferior. Thus Fanon believed that: Fanon mentions a theory of collective catharsis when he talks about educational and recreational books and magazines for children.
Therefore when an Antillean boys and girls identifies themselves with the 5 Frantz Fanon, Peau noire, masques blancs p.
We are also given examples of black women who would dream about magically turning white, and who would never consider it possible to date a black man, because the whiter the better, even though it is commonly know there is not many success stories of such relationships. Because white men see black man as savage and primitive, they give them certain qualities that they do not posses.
What he means by this is that a white man does not know he is white until he is presented with the concept of a black man or someone with a different skin colour. Fanon believed that the notion of racial differences was unconsciously implanted in the minds of the people through media and education among other institutes in society. This racial propaganda, however, was internalised by both whites and blacks and therefore they both have the same idea of white mans supremacy and black mans inferiority.
Furthermore, Fanon believed that language contributes to the racialising process as by speaking the language of the oppressor, the oppressed looses the sense of self by accepting the racial supremacy of the white man.
He also believed that as the feeling of inferiority appears in correspondence to the feeling of superiority, that is that both black man and white man are imprisoned in socially contracted racial structures. Both Fanon and Hegel believed that the only possible way of breaking this vicious circle 10 Frantz Fanon, Peau noire, masques blancs p.
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In Peau noire, masques blancs Fanon shows that there is more to racism than merely one race asserting itself over another, he clearly highlights the psychological, social and historical roles that are attributed to the processes of racialization and the implications that it has on both the oppressor and the oppressed. Remember me on this computer. Enter the email address you signed up with and we’ll email you a reset link. Click here to sign up. Help Center Find new research papers in:
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